Assessing the genetic contribution of Neanderthals to non-disease phenotypes in modern humans has been difficult because of the absence of large cohorts for which common phenotype information is available. Neanderthal alleles contributed more variation in four behavioral phenotypes influencing sleep, mood, and smoking behaviors, suggesting that Neanderthal alleles contribute more to these traits than expected from their frequency in modern humans. The Contribution of Neanderthals to Phenotypic Variation in Modern Humans, https://doi.org/10.1016/j.ajhg.2017.09.010.
We use cookies to help provide and enhance our service and tailor content and ads. Here, we show that Neanderthal DNA affects skin tone and hair color, height, sleeping patterns, mood, and smoking status in present-day Europeans.
Using baseline phenotypes collected for 112,000 individuals by the UK Biobank, we can now elaborate on previous findings that identified associations between signatures of positive selection on …
Interestingly, multiple Neanderthal alleles at different loci contribute to skin and hair color in present-day Europeans, and these Neanderthal alleles contribute to both lighter and darker skin tones and hair color, suggesting that Neanderthals themselves were most likely variable in these traits. The Contribution of Neanderthals to Phenotypic Variation in Modern Humans Michael Dannemann 1and Janet Kelso ,* Assessing the genetic contribution of Neanderthals to non-disease phenotypes in modern humans has been difficult because of the absence of large cohorts for which common phenotype information is available. Interestingly, multiple Neanderthal alleles at different loci contribute to skin and hair color in present-day Europeans, and these Neanderthal alleles contribute to both lighter and darker skin tones and hair color, suggesting that Neanderthals themselves were most likely variable in these traits.
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Assessing the genetic contribution of Neanderthals to non-disease phenotypes in modern humans has been difficult because of the absence of large cohorts for which common phenotype information is available.
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ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. By continuing you agree to the use of cookies. Assessing the genetic contribution of Neanderthals to non-disease phenotypes in modern humans has been difficult because of the absence of large cohorts for which common phenotype information is available. 832 0 obj
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Neanderthal alleles contributed more variation in four behavioral phenotypes influencing sleep, mood, and smoking behaviors, suggesting that Neanderthal alleles contribute more to these traits than expected from their frequency in modern humans. h�b```���@2�A�D�bl,3�$)�0�\�*aؼ�'�_��|�����~\`wb``a���怾 �+=C�k�%��2�0��f�X�~��{��`��o����$K3�T 5��1���� 䄲ؖi������:N>g���:!�_����7t�oN��xۘXT6�r�dyBD��I�S��S&������/��4�qB��a?8��K�ɭ̗�b�͋ʸ��tY/ƪu@���e���Ee���t,J�|�kQl@� &�D��m���:�2@9F ���(��`�� �aGp)&
� ԉ`hG0=^�ŀ����s�a~�|��)�uY>�4� fn��\y»����/0,f�����Q������9S>&��]���I�z��0�K}�p�a���@��33��9�p�a�$�5. Using baseline phenotypes collected for 112,000 individuals by the UK Biobank, we can now elaborate on previous findings that identified associations between signatures of positive selection on … Here, we show that Neanderthal DNA affects skin tone and hair color, height, sleeping patterns, mood, and smoking status in present-day Europeans. endstream
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The Contribution of Neanderthals to Phenotypic Variation in Modern Humans, https://doi.org/10.1016/j.ajhg.2017.09.010. Using baseline phenotypes collected for 112,000 individuals by the UK Biobank, we can now elaborate on previous findings that identified associations between signatures of positive selection on Neanderthal DNA and various modern human traits but not any specific phenotypic consequences. Using baseline phenotypes collected for 112,000 individuals by the UK Biobank, we can now elaborate on previous findings that identified associations between signatures of positive selection on Neanderthal DNA and various modern human traits but not any specific phenotypic consequences. Using baseline phenotypes collected for 112,000 %%EOF
Assessing the genetic contribution of Neanderthals to non-disease phenotypes in modern humans has been difficult because of the absence of large cohorts for which common phenotype information is available.
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