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Clipboard, Search History, and several other advanced features are temporarily unavailable. This approach works even when little or no information is available about the biochemical basis of the disease. Northern hybridization revealed that the VLDLR messenger RNA (mRNA) is most abundant in skeletal muscle, heart, kidney, and brain.
2011 Mar 1;3(3):a004069.
The availability of a murine complementary DNA probe and the knowledge of the map position of the VLDLR gene in the mouse genome will facilitate studies on the function and regulation of this protein. Clipboard, Search History, and several other advanced features are temporarily unavailable.
Positional cloning is used in conjunction with linkage analysis. Identification and characterization of a Na(+)-independent neutral amino acid transporter that associates with the 4F2 heavy chain and exhibits substrate selectivity for small neutral D- and L-amino acids.
2020 Mar;99(3):1628-1642. doi: 10.1016/j.psj.2019.10.057. Click chemistry based biopolymeric hydrogels for regenerative medicine. Levels of VLDLR mRNA in mouse placenta increased from days 8-18 of gestation. Hofmann SL(1), Topham M, Hsieh CL, Francke U. 2001 Jun 15;74(3):262-72. doi: 10.1006/geno.2001.6567. A clone is a genetically identical copy of an organism, and it may be naturally occurring or created in the lab. Because of the high-affinity transport with the K(m) value close to the physiological concentration of D-serine, together with the high levels of expression in brain, hAsc-1 is proposed to play significant roles in the D-serine mobilization in brain. 1985;3:311-47. doi: 10.1080/02648725.1985.10647817. Xie P, Han MX, Chen WX, Wan XP, Xu YG, Gong DQ. Please enable it to take advantage of the complete set of features! Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. doi: 10.1161/JAHA.113.000460. This site needs JavaScript to work properly. | An interplay of structure and intrinsic disorder in the functionality of peptidylarginine deiminases, a family of key autoimmunity-related enzymes.
EMBO Rep. 2018 Sep;19(9):e43879. USA.gov. You do not currently have access to this article. Identification and functional characterization of a Na+-independent neutral amino acid transporter with broad substrate selectivity. Segawa H, Fukasawa Y, Miyamoto K, Takeda E, Endou H, Kanai Y. J Biol Chem. This probe may be used to identify a gene on chromosome 19 adjacent to the breakpoint that can contribute to the malignant development of B lymphocytes. NIH Because of the high-affinity transport with the K(m) value close to the physiological concentration of D-serine, together with the high levels of expression in brain, hAsc-1 is proposed to play significant roles in the D-serine mobilization in brain.
Poult Sci. | hAsc-1 transported D-serine at high affinity with a K(m) value of 22.8 microM.
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